Target name

P18901: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P18901
GRCP SARfari Variant Name rDRD1_1375
PDB ID
DrugBank ID
BioGrid ID 246496
GuidetoPHARMACOLOGY ID 214
PharmGKB ID
KEGG ID
Entrez Gene (Gene ID)
BindingDB P18901

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.74 0.73 0.74 0.74 0.81 0.48 Download
FP4 fingerprints 0.780 0.700 0.740 0.750 0.810 0.480 Download
MACCS fingerprints 0.810 0.670 0.740 0.760 0.810 0.490 Download
Daylight fingerprints 0.680 0.670 0.670 0.670 0.750 0.340 Download
ECFP2 fingerprints 0.890 0.730 0.810 0.820 0.870 0.620 Download
ECFP4 fingerprints 0.910 0.780 0.840 0.850 0.900 0.690 Download
ECFP6 fingerprints 0.880 0.800 0.840 0.850 0.900 0.680 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn