Target name

P19020: D(3) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).

  Database links

Uniprot primary ID P19020
GRCP SARfari Variant Name rDRD3_1376
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 216
PharmGKB ID
KEGG ID rno:29238
Entrez Gene (Gene ID) 29238
BindingDB P19020

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.87 0.73 0.8 0.82 0.88 0.61 Download
FP4 fingerprints 0.860 0.720 0.790 0.800 0.860 0.580 Download
MACCS fingerprints 0.870 0.710 0.790 0.810 0.850 0.590 Download
Daylight fingerprints 0.840 0.660 0.750 0.770 0.790 0.510 Download
ECFP2 fingerprints 0.950 0.770 0.860 0.870 0.930 0.740 Download
ECFP4 fingerprints 0.950 0.840 0.890 0.900 0.950 0.790 Download
ECFP6 fingerprints 0.920 0.860 0.890 0.890 0.950 0.780 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn