Target name

P20272: Cannabinoid receptor 1


  Protein function

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca

  Database links

Uniprot primary ID P20272
GRCP SARfari Variant Name rCB1R_1379
PDB ID
DrugBank ID
BioGrid ID 247288
GuidetoPHARMACOLOGY ID 56
PharmGKB ID
KEGG ID rno:25248
Entrez Gene (Gene ID) 25248
BindingDB P20272

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.5 0.96 0.73 0.65 0.92 0.51 Download
FP4 fingerprints 0.790 0.830 0.810 0.810 0.900 0.620 Download
MACCS fingerprints 0.800 0.790 0.800 0.800 0.880 0.590 Download
Daylight fingerprints 0.590 0.830 0.710 0.670 0.740 0.430 Download
ECFP2 fingerprints 0.860 0.900 0.880 0.880 0.950 0.760 Download
ECFP4 fingerprints 0.880 0.930 0.900 0.900 0.960 0.810 Download
ECFP6 fingerprints 0.850 0.940 0.890 0.890 0.960 0.790 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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