Target name

P20288: D(2) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P20288
GRCP SARfari Variant Name bDRD2_1380
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281126
Entrez Gene (Gene ID) 281126
BindingDB P20288

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.68 0.76 0.78 0.81 0.54 Download
FP4 fingerprints 0.840 0.630 0.740 0.760 0.800 0.480 Download
MACCS fingerprints 0.820 0.660 0.740 0.760 0.800 0.490 Download
Daylight fingerprints 0.690 0.650 0.670 0.680 0.730 0.340 Download
ECFP2 fingerprints 0.860 0.610 0.730 0.760 0.820 0.480 Download
ECFP4 fingerprints 0.910 0.730 0.820 0.840 0.900 0.660 Download
ECFP6 fingerprints 0.900 0.780 0.840 0.850 0.900 0.680 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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