Target name

P21462: fMet-Leu-Phe receptor


  Protein function

High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:

  Database links

Uniprot primary ID P21462
GRCP SARfari Variant Name hFPR1_101
PDB ID
DrugBank ID DB00716
BioGrid ID 108640
GuidetoPHARMACOLOGY ID 222
PharmGKB ID PA28244
KEGG ID hsa:2357
Entrez Gene (Gene ID) 2357
BindingDB P21462

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.83 0.76 0.79 0.8 0.81 0.59 Download
FP4 fingerprints 0.690 0.790 0.740 0.730 0.750 0.480 Download
MACCS fingerprints 0.690 0.790 0.740 0.730 0.770 0.480 Download
Daylight fingerprints 0.700 0.770 0.730 0.730 0.780 0.470 Download
ECFP2 fingerprints 0.720 0.770 0.740 0.740 0.730 0.490 Download
ECFP4 fingerprints 0.770 0.780 0.770 0.770 0.810 0.540 Download
ECFP6 fingerprints 0.780 0.790 0.780 0.780 0.820 0.560 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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