Target name

P21730: C5a anaphylatoxin chemotactic receptor 1


  Protein function

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:

  Database links

Uniprot primary ID P21730
GRCP SARfari Variant Name hC5R1_104
PDB ID
DrugBank ID
BioGrid ID 107189
GuidetoPHARMACOLOGY ID 32
PharmGKB ID PA25920
KEGG ID hsa:728
Entrez Gene (Gene ID) 728
BindingDB P21730

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.85 0.77 0.81 0.82 0.83 0.62 Download
FP4 fingerprints 0.770 0.690 0.730 0.740 0.800 0.460 Download
MACCS fingerprints 0.850 0.600 0.730 0.760 0.780 0.470 Download
Daylight fingerprints 0.820 0.700 0.760 0.770 0.790 0.520 Download
ECFP2 fingerprints 0.860 0.780 0.820 0.830 0.840 0.640 Download
ECFP4 fingerprints 0.870 0.800 0.830 0.840 0.880 0.670 Download
ECFP6 fingerprints 0.860 0.800 0.830 0.830 0.870 0.660 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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