Target name

P21918: D(1B) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P21918
GRCP SARfari Variant Name hDRD5_107
PDB ID
DrugBank ID DB06148 DB01624 DB01238 DB01235 DB00568 DB00408 DB00370 DB01403 DB00268 DB00589 DB00334 DB05271 DB00726 DB00800 DB00413 DB01200 DB00458 DB01186 DB00696 DB00477 DB00988 DB01224 DB00714 DB00246 DB00248
BioGrid ID 108150
GuidetoPHARMACOLOGY ID 218
PharmGKB ID PA148
KEGG ID hsa:1816
Entrez Gene (Gene ID) 1816
BindingDB P21918

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.81 0.75 0.78 0.78 0.82 0.55 Download
FP4 fingerprints 0.840 0.620 0.730 0.750 0.780 0.460 Download
MACCS fingerprints 0.710 0.700 0.700 0.710 0.790 0.410 Download
Daylight fingerprints 0.650 0.630 0.640 0.650 0.710 0.280 Download
ECFP2 fingerprints 0.810 0.540 0.680 0.710 0.780 0.360 Download
ECFP4 fingerprints 0.860 0.730 0.790 0.800 0.890 0.590 Download
ECFP6 fingerprints 0.840 0.810 0.830 0.830 0.900 0.650 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn