Target name

P23944: Alpha-1D adrenergic receptor


  Protein function

This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

  Database links

Uniprot primary ID P23944
GRCP SARfari Variant Name rA1AD_1393
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 24
PharmGKB ID
KEGG ID rno:29413
Entrez Gene (Gene ID) 29413
BindingDB P23944

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.77 0.72 0.74 0.75 0.83 0.49 Download
FP4 fingerprints 0.770 0.660 0.710 0.730 0.800 0.430 Download
MACCS fingerprints 0.770 0.640 0.700 0.720 0.770 0.410 Download
Daylight fingerprints 0.680 0.660 0.670 0.670 0.720 0.340 Download
ECFP2 fingerprints 0.860 0.770 0.810 0.820 0.890 0.630 Download
ECFP4 fingerprints 0.870 0.830 0.850 0.850 0.920 0.700 Download
ECFP6 fingerprints 0.830 0.850 0.840 0.840 0.920 0.690 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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