Target name

P25095: Type-1A angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P25095
GRCP SARfari Variant Name rAGTR1A_1396
PDB ID 2AC6 2AH3
DrugBank ID
BioGrid ID 246370
GuidetoPHARMACOLOGY ID 34
PharmGKB ID
KEGG ID rno:24180
Entrez Gene (Gene ID) 24180
BindingDB P25095

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.89 0.93 0.91 0.9 0.95 0.81 Download
FP4 fingerprints 0.910 0.830 0.870 0.870 0.930 0.740 Download
MACCS fingerprints 0.860 0.880 0.870 0.870 0.940 0.740 Download
Daylight fingerprints 0.890 0.870 0.880 0.880 0.920 0.760 Download
ECFP2 fingerprints 0.930 0.910 0.920 0.920 0.950 0.840 Download
ECFP4 fingerprints 0.940 0.920 0.930 0.930 0.950 0.860 Download
ECFP6 fingerprints 0.930 0.930 0.930 0.930 0.950 0.860 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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