Target name

P25099: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P25099
GRCP SARfari Variant Name rAA1_1397
PDB ID
DrugBank ID
BioGrid ID 247960
GuidetoPHARMACOLOGY ID 18
PharmGKB ID
KEGG ID rno:29290
Entrez Gene (Gene ID) 29290
BindingDB P25099

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.86 0.83 0.85 0.85 0.89 0.7 Download
FP4 fingerprints 0.890 0.780 0.840 0.840 0.880 0.670 Download
MACCS fingerprints 0.880 0.790 0.840 0.840 0.870 0.670 Download
Daylight fingerprints 0.760 0.810 0.790 0.780 0.850 0.570 Download
ECFP2 fingerprints 0.880 0.840 0.860 0.860 0.920 0.720 Download
ECFP4 fingerprints 0.860 0.860 0.860 0.860 0.930 0.720 Download
ECFP6 fingerprints 0.820 0.880 0.850 0.850 0.920 0.700 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn