Target name

P25104: Type-1 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P25104
GRCP SARfari Variant Name bAGTR1A_1399
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281607
Entrez Gene (Gene ID) 281607
BindingDB P25104

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.95 0.94 0.95 0.95 0.97 0.9 Download
FP4 fingerprints 0.920 0.890 0.910 0.910 0.960 0.810 Download
MACCS fingerprints 0.920 0.930 0.930 0.930 0.960 0.850 Download
Daylight fingerprints 0.930 0.940 0.940 0.940 0.950 0.870 Download
ECFP2 fingerprints 0.960 0.940 0.950 0.950 0.980 0.900 Download
ECFP4 fingerprints 0.960 0.940 0.950 0.950 0.980 0.910 Download
ECFP6 fingerprints 0.960 0.940 0.950 0.950 0.980 0.900 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn