Target name

P25115: D(1B) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P25115
GRCP SARfari Variant Name rDRD5_1400
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 218
PharmGKB ID
KEGG ID rno:25195
Entrez Gene (Gene ID) 25195
BindingDB P25115

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.86 0.75 0.8 0.81 0.88 0.61 Download
FP4 fingerprints 0.920 0.700 0.810 0.830 0.840 0.640 Download
MACCS fingerprints 0.840 0.680 0.760 0.780 0.830 0.530 Download
Daylight fingerprints 0.800 0.690 0.740 0.760 0.820 0.490 Download
ECFP2 fingerprints 0.950 0.770 0.860 0.870 0.910 0.730 Download
ECFP4 fingerprints 0.960 0.820 0.890 0.900 0.940 0.790 Download
ECFP6 fingerprints 0.950 0.850 0.900 0.900 0.940 0.800 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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