Target name

P28190: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P28190
GRCP SARfari Variant Name bAA1_1406
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:282133
Entrez Gene (Gene ID) 282133
BindingDB P28190

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.94 0.83 0.88 0.89 0.92 0.77 Download
FP4 fingerprints 0.970 0.790 0.880 0.890 0.910 0.770 Download
MACCS fingerprints 0.890 0.800 0.840 0.850 0.890 0.690 Download
Daylight fingerprints 0.840 0.770 0.810 0.810 0.850 0.610 Download
ECFP2 fingerprints 0.980 0.790 0.880 0.890 0.930 0.780 Download
ECFP4 fingerprints 0.980 0.820 0.900 0.910 0.950 0.810 Download
ECFP6 fingerprints 0.960 0.850 0.910 0.910 0.950 0.820 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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