Target name

P28647: Adenosine receptor A3


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.

  Database links

Uniprot primary ID P28647
GRCP SARfari Variant Name rAA3_1411
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 21
PharmGKB ID
KEGG ID rno:100911796,rno:25370
Entrez Gene (Gene ID) 1.0036317825e+022
BindingDB P28647

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.81 0.78 0.79 0.8 0.85 0.59 Download
FP4 fingerprints 0.790 0.770 0.780 0.780 0.860 0.560 Download
MACCS fingerprints 0.810 0.770 0.790 0.790 0.840 0.580 Download
Daylight fingerprints 0.810 0.800 0.800 0.800 0.840 0.610 Download
ECFP2 fingerprints 0.840 0.760 0.800 0.810 0.880 0.600 Download
ECFP4 fingerprints 0.830 0.790 0.810 0.810 0.900 0.620 Download
ECFP6 fingerprints 0.820 0.850 0.830 0.830 0.900 0.660 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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