Target name

P29089: Type-1B angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P29089
GRCP SARfari Variant Name rAGTR1B_1412
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 34
PharmGKB ID
KEGG ID rno:81638
Entrez Gene (Gene ID) 81638
BindingDB P29089

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.9 0.91 0.9 0.9 0.94 0.8 Download
FP4 fingerprints 0.900 0.810 0.850 0.860 0.920 0.710 Download
MACCS fingerprints 0.890 0.870 0.880 0.880 0.940 0.760 Download
Daylight fingerprints 0.880 0.840 0.860 0.860 0.900 0.730 Download
ECFP2 fingerprints 0.930 0.900 0.910 0.920 0.950 0.830 Download
ECFP4 fingerprints 0.930 0.910 0.920 0.920 0.960 0.850 Download
ECFP6 fingerprints 0.930 0.910 0.920 0.920 0.950 0.850 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn