Target name

P29275: Adenosine receptor A2b


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P29275
GRCP SARfari Variant Name hAA2B_130
PDB ID
DrugBank ID DB00640 DB00824 DB00277 DB04932
BioGrid ID 106648
GuidetoPHARMACOLOGY ID 20
PharmGKB ID PA24585
KEGG ID hsa:136
Entrez Gene (Gene ID) 136
BindingDB P29275

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.81 0.81 0.81 0.81 0.89 0.62 Download
FP4 fingerprints 0.750 0.800 0.770 0.770 0.860 0.550 Download
MACCS fingerprints 0.810 0.690 0.750 0.770 0.840 0.510 Download
Daylight fingerprints 0.790 0.720 0.760 0.760 0.820 0.510 Download
ECFP2 fingerprints 0.850 0.800 0.830 0.830 0.910 0.660 Download
ECFP4 fingerprints 0.810 0.870 0.840 0.840 0.920 0.680 Download
ECFP6 fingerprints 0.770 0.880 0.830 0.820 0.920 0.660 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn