Target name

P29276: Adenosine receptor A2b


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P29276
GRCP SARfari Variant Name rAA2B_1413
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 20
PharmGKB ID
KEGG ID rno:29316
Entrez Gene (Gene ID) 29316
BindingDB P29276

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.76 0.8 0.81 0.86 0.6 Download
FP4 fingerprints 0.910 0.700 0.810 0.820 0.870 0.630 Download
MACCS fingerprints 0.830 0.750 0.790 0.800 0.860 0.580 Download
Daylight fingerprints 0.820 0.810 0.810 0.810 0.850 0.620 Download
ECFP2 fingerprints 0.880 0.750 0.810 0.830 0.880 0.630 Download
ECFP4 fingerprints 0.870 0.790 0.830 0.840 0.890 0.670 Download
ECFP6 fingerprints 0.830 0.810 0.820 0.820 0.890 0.640 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn