Target name

P30411: B2 bradykinin receptor


  Protein function

Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P30411
GRCP SARfari Variant Name hB2R_133
PDB ID
DrugBank ID DB06196
BioGrid ID 107093
GuidetoPHARMACOLOGY ID 42
PharmGKB ID PA80
KEGG ID hsa:624
Entrez Gene (Gene ID) 624
BindingDB P30411

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.73 0.97 0.85 0.83 0.95 0.71 Download
FP4 fingerprints 0.840 0.910 0.870 0.870 0.930 0.750 Download
MACCS fingerprints 0.780 0.880 0.830 0.820 0.910 0.660 Download
Daylight fingerprints 0.760 0.950 0.860 0.840 0.910 0.720 Download
ECFP2 fingerprints 0.880 0.960 0.920 0.910 0.970 0.840 Download
ECFP4 fingerprints 0.880 0.970 0.930 0.920 0.980 0.860 Download
ECFP6 fingerprints 0.870 0.980 0.930 0.920 0.980 0.860 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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