Target name

P30542: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P30542
GRCP SARfari Variant Name hAA1_135
PDB ID
DrugBank ID DB00996 DB00651 DB00640 DB01223 DB01412 DB00201 DB00824 DB00806 DB04932 DB01303 DB00277
BioGrid ID 106646
GuidetoPHARMACOLOGY ID 18
PharmGKB ID PA24583
KEGG ID hsa:134
Entrez Gene (Gene ID) 134
BindingDB P30542

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.88 0.79 0.84 0.84 0.89 0.68 Download
FP4 fingerprints 0.870 0.720 0.790 0.810 0.850 0.590 Download
MACCS fingerprints 0.880 0.750 0.810 0.820 0.860 0.630 Download
Daylight fingerprints 0.780 0.750 0.760 0.770 0.810 0.530 Download
ECFP2 fingerprints 0.940 0.770 0.860 0.870 0.910 0.720 Download
ECFP4 fingerprints 0.910 0.820 0.870 0.870 0.920 0.730 Download
ECFP6 fingerprints 0.870 0.830 0.850 0.850 0.920 0.710 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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