Target name

P30543: Adenosine receptor A2a


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P30543
GRCP SARfari Variant Name rAA2A_1416
PDB ID
DrugBank ID
BioGrid ID 247408
GuidetoPHARMACOLOGY ID 19
PharmGKB ID
KEGG ID rno:25369
Entrez Gene (Gene ID) 25369
BindingDB P30543

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.89 0.79 0.84 0.85 0.88 0.69 Download
FP4 fingerprints 0.890 0.740 0.820 0.830 0.860 0.640 Download
MACCS fingerprints 0.860 0.760 0.810 0.820 0.870 0.620 Download
Daylight fingerprints 0.810 0.780 0.800 0.800 0.850 0.600 Download
ECFP2 fingerprints 0.870 0.790 0.830 0.840 0.900 0.670 Download
ECFP4 fingerprints 0.860 0.830 0.840 0.840 0.910 0.690 Download
ECFP6 fingerprints 0.820 0.850 0.830 0.830 0.910 0.670 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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