Target name

P30556: Type-1 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P30556
GRCP SARfari Variant Name hAGTR1A_137
PDB ID 1ZV0 4YAY
DrugBank ID DB01029 DB00876 DB01349 DB00678 DB08822 DB01347 DB00796 DB00966 DB01342 DB00177 DB00275
BioGrid ID 106691
GuidetoPHARMACOLOGY ID 34
PharmGKB ID PA43
KEGG ID hsa:185
Entrez Gene (Gene ID) 185
BindingDB P30556

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.96 0.9 0.89 0.94 0.81 Download
FP4 fingerprints 0.860 0.820 0.840 0.850 0.920 0.690 Download
MACCS fingerprints 0.830 0.880 0.850 0.850 0.910 0.710 Download
Daylight fingerprints 0.830 0.850 0.840 0.840 0.860 0.680 Download
ECFP2 fingerprints 0.880 0.960 0.920 0.920 0.950 0.840 Download
ECFP4 fingerprints 0.880 0.970 0.920 0.920 0.950 0.850 Download
ECFP6 fingerprints 0.870 0.980 0.920 0.920 0.950 0.850 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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