Target name

P30559: Oxytocin receptor


  Protein function

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P30559
GRCP SARfari Variant Name hOXTR_138
PDB ID
DrugBank ID DB01282 DB00107
BioGrid ID 111061
GuidetoPHARMACOLOGY ID 369
PharmGKB ID PA32858
KEGG ID hsa:5021
Entrez Gene (Gene ID) 5021
BindingDB P30559

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.82 0.9 0.86 0.85 0.94 0.72 Download
FP4 fingerprints 0.830 0.810 0.820 0.820 0.890 0.640 Download
MACCS fingerprints 0.870 0.680 0.770 0.790 0.870 0.560 Download
Daylight fingerprints 0.840 0.750 0.790 0.800 0.840 0.590 Download
ECFP2 fingerprints 0.900 0.890 0.900 0.900 0.950 0.790 Download
ECFP4 fingerprints 0.900 0.950 0.930 0.930 0.970 0.860 Download
ECFP6 fingerprints 0.860 0.960 0.910 0.900 0.970 0.820 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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