Target name

P30872: Somatostatin receptor type 1


  Protein function

Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na

  Database links

Uniprot primary ID P30872
GRCP SARfari Variant Name hSSTR1_139
PDB ID
DrugBank ID DB00104 DB06663
BioGrid ID 112629
GuidetoPHARMACOLOGY ID 355
PharmGKB ID PA36154
KEGG ID hsa:6751
Entrez Gene (Gene ID) 6751
BindingDB P30872

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.89 0.87 0.86 0.92 0.74 Download
FP4 fingerprints 0.840 0.910 0.870 0.870 0.930 0.750 Download
MACCS fingerprints 0.840 0.900 0.870 0.870 0.890 0.740 Download
Daylight fingerprints 0.850 0.890 0.870 0.870 0.910 0.740 Download
ECFP2 fingerprints 0.840 0.920 0.880 0.880 0.940 0.760 Download
ECFP4 fingerprints 0.830 0.940 0.880 0.870 0.950 0.770 Download
ECFP6 fingerprints 0.800 0.940 0.870 0.860 0.950 0.750 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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