Target name

P32247: Bombesin receptor subtype-3


  Protein function

Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P32247
GRCP SARfari Variant Name hBRS3_150
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 40
PharmGKB ID PA25427
KEGG ID hsa:680
Entrez Gene (Gene ID) 680
BindingDB P32247

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.87 0.92 0.89 0.89 0.92 0.79 Download
FP4 fingerprints 0.890 0.830 0.860 0.870 0.920 0.730 Download
MACCS fingerprints 0.800 0.900 0.850 0.840 0.930 0.710 Download
Daylight fingerprints 0.860 0.880 0.870 0.870 0.890 0.740 Download
ECFP2 fingerprints 0.870 0.870 0.870 0.870 0.920 0.740 Download
ECFP4 fingerprints 0.880 0.920 0.900 0.900 0.930 0.800 Download
ECFP6 fingerprints 0.860 0.940 0.900 0.890 0.930 0.800 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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