Target name

P32745: Somatostatin receptor type 3


  Protein function

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

  Database links

Uniprot primary ID P32745
GRCP SARfari Variant Name hSSTR3_154
PDB ID
DrugBank ID DB06663
BioGrid ID 112631
GuidetoPHARMACOLOGY ID 357
PharmGKB ID PA36156
KEGG ID hsa:6753
Entrez Gene (Gene ID) 6753
BindingDB P32745

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.81 0.94 0.87 0.87 0.94 0.75 Download
FP4 fingerprints 0.820 0.950 0.890 0.880 0.960 0.780 Download
MACCS fingerprints 0.810 0.950 0.880 0.870 0.890 0.760 Download
Daylight fingerprints 0.810 0.930 0.870 0.860 0.930 0.750 Download
ECFP2 fingerprints 0.810 0.940 0.880 0.870 0.970 0.760 Download
ECFP4 fingerprints 0.800 0.960 0.880 0.870 0.970 0.770 Download
ECFP6 fingerprints 0.790 0.970 0.880 0.860 0.970 0.770 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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