Target name

P33765: Adenosine receptor A3


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.

  Database links

Uniprot primary ID P33765
GRCP SARfari Variant Name hAA3_156
PDB ID 1OEA 1R7N
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID PA24589
KEGG ID hsa:140
Entrez Gene (Gene ID) 140
BindingDB P0DMS8

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.83 0.79 0.81 0.82 0.87 0.62 Download
FP4 fingerprints 0.850 0.740 0.790 0.800 0.850 0.590 Download
MACCS fingerprints 0.840 0.770 0.800 0.810 0.850 0.610 Download
Daylight fingerprints 0.780 0.750 0.760 0.760 0.800 0.520 Download
ECFP2 fingerprints 0.910 0.790 0.850 0.860 0.900 0.710 Download
ECFP4 fingerprints 0.880 0.840 0.860 0.860 0.910 0.720 Download
ECFP6 fingerprints 0.850 0.850 0.850 0.850 0.910 0.700 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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