Target name

P34972: Cannabinoid receptor 2


  Protein function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.

  Database links

Uniprot primary ID P34972
GRCP SARfari Variant Name hCB2R_158
PDB ID 2KI9
DrugBank ID DB00470 DB00486
BioGrid ID
GuidetoPHARMACOLOGY ID 57
PharmGKB ID PA26682
KEGG ID hsa:1269
Entrez Gene (Gene ID) 1269
BindingDB P34972

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.75 0.83 0.79 0.78 0.88 0.59 Download
FP4 fingerprints 0.770 0.750 0.760 0.760 0.830 0.520 Download
MACCS fingerprints 0.740 0.690 0.720 0.720 0.790 0.430 Download
Daylight fingerprints 0.710 0.670 0.690 0.690 0.730 0.380 Download
ECFP2 fingerprints 0.830 0.820 0.820 0.830 0.910 0.650 Download
ECFP4 fingerprints 0.880 0.880 0.880 0.880 0.940 0.760 Download
ECFP6 fingerprints 0.870 0.880 0.880 0.880 0.940 0.750 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn