Target name

P34976: Type-1 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P34976
GRCP SARfari Variant Name orAGTR1A_1468
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ocu:100009164
Entrez Gene (Gene ID) 100009164
BindingDB P34976

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.97 0.96 0.96 0.96 0.98 0.92 Download
FP4 fingerprints 0.970 0.910 0.940 0.940 0.990 0.880 Download
MACCS fingerprints 0.850 0.940 0.900 0.890 0.960 0.790 Download
Daylight fingerprints 0.970 0.970 0.970 0.970 0.980 0.940 Download
ECFP2 fingerprints 0.970 0.940 0.950 0.960 0.990 0.910 Download
ECFP4 fingerprints 0.980 0.950 0.970 0.970 0.990 0.930 Download
ECFP6 fingerprints 0.970 0.950 0.960 0.960 0.990 0.920 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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