Target name

P35346: Somatostatin receptor type 5


  Protein function

Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization.

  Database links

Uniprot primary ID P35346
GRCP SARfari Variant Name hSSTR5_161
PDB ID
DrugBank ID DB00104 DB06663 DB04894
BioGrid ID 112633
GuidetoPHARMACOLOGY ID 359
PharmGKB ID PA36158
KEGG ID hsa:6755
Entrez Gene (Gene ID) 6755
BindingDB P35346

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.74 0.91 0.83 0.81 0.91 0.66 Download
FP4 fingerprints 0.760 0.930 0.850 0.840 0.930 0.710 Download
MACCS fingerprints 0.770 0.910 0.840 0.830 0.900 0.680 Download
Daylight fingerprints 0.740 0.910 0.820 0.810 0.900 0.660 Download
ECFP2 fingerprints 0.740 0.930 0.840 0.820 0.940 0.690 Download
ECFP4 fingerprints 0.720 0.950 0.840 0.820 0.960 0.700 Download
ECFP6 fingerprints 0.710 0.960 0.830 0.810 0.950 0.690 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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