Target name

P35351: Type-2 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity).

  Database links

Uniprot primary ID P35351
GRCP SARfari Variant Name rAGTR2_1474
PDB ID 2G2A
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 35
PharmGKB ID
KEGG ID rno:24182
Entrez Gene (Gene ID) 24182
BindingDB P35351

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.89 0.81 0.85 0.85 0.9 0.7 Download
FP4 fingerprints 0.890 0.730 0.810 0.820 0.890 0.630 Download
MACCS fingerprints 0.690 0.810 0.750 0.730 0.850 0.510 Download
Daylight fingerprints 0.870 0.800 0.840 0.840 0.860 0.670 Download
ECFP2 fingerprints 0.900 0.800 0.850 0.860 0.930 0.710 Download
ECFP4 fingerprints 0.930 0.820 0.880 0.880 0.940 0.760 Download
ECFP6 fingerprints 0.890 0.840 0.860 0.870 0.940 0.730 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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