Target name

P35463: Endothelin B receptor


  Protein function

Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P35463
GRCP SARfari Variant Name susETBR_1489
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ssc:414911
Entrez Gene (Gene ID) 414911
BindingDB P35463

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.76 0.82 0.79 0.78 0.88 0.58 Download
FP4 fingerprints 0.700 0.800 0.750 0.730 0.880 0.500 Download
MACCS fingerprints 0.730 0.850 0.790 0.780 0.880 0.590 Download
Daylight fingerprints 0.760 0.870 0.810 0.800 0.900 0.630 Download
ECFP2 fingerprints 0.890 0.810 0.850 0.860 0.910 0.700 Download
ECFP4 fingerprints 0.940 0.820 0.880 0.890 0.930 0.760 Download
ECFP6 fingerprints 0.960 0.830 0.900 0.900 0.930 0.800 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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