Target name

P37288: Vasopressin V1a receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.

  Database links

Uniprot primary ID P37288
GRCP SARfari Variant Name hAVPR1A_171
PDB ID 1YTV
DrugBank ID DB02638 DB00093 DB00872 DB06212 DB00067 DB00035
BioGrid ID 107033
GuidetoPHARMACOLOGY ID 366
PharmGKB ID PA25187
KEGG ID hsa:552
Entrez Gene (Gene ID) 552
BindingDB P37288

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.79 0.88 0.84 0.83 0.92 0.68 Download
FP4 fingerprints 0.730 0.830 0.780 0.770 0.850 0.560 Download
MACCS fingerprints 0.830 0.710 0.770 0.780 0.870 0.550 Download
Daylight fingerprints 0.780 0.740 0.760 0.770 0.830 0.520 Download
ECFP2 fingerprints 0.800 0.900 0.850 0.850 0.930 0.710 Download
ECFP4 fingerprints 0.830 0.940 0.890 0.880 0.950 0.780 Download
ECFP6 fingerprints 0.810 0.960 0.880 0.880 0.950 0.780 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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