Target name

P43119: Prostacyclin receptor


  Protein function

Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

  Database links

Uniprot primary ID P43119
GRCP SARfari Variant Name hPTGIR_182
PDB ID
DrugBank ID DB01160 DB01088 DB01240 DB00374
BioGrid ID 111711
GuidetoPHARMACOLOGY ID 345
PharmGKB ID PA291
KEGG ID hsa:5739
Entrez Gene (Gene ID) 5739
BindingDB P43119

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.76 0.87 0.82 0.81 0.87 0.64 Download
FP4 fingerprints 0.800 0.750 0.780 0.780 0.820 0.560 Download
MACCS fingerprints 0.690 0.820 0.760 0.740 0.820 0.520 Download
Daylight fingerprints 0.760 0.870 0.820 0.810 0.850 0.640 Download
ECFP2 fingerprints 0.780 0.750 0.770 0.770 0.830 0.530 Download
ECFP4 fingerprints 0.800 0.800 0.800 0.800 0.880 0.600 Download
ECFP6 fingerprints 0.780 0.830 0.810 0.800 0.880 0.610 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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