Target name

P46663: B1 bradykinin receptor


  Protein function

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

  Database links

Uniprot primary ID P46663
GRCP SARfari Variant Name hBDKRB1_190
PDB ID
DrugBank ID
BioGrid ID 107092
GuidetoPHARMACOLOGY ID 41
PharmGKB ID PA79
KEGG ID hsa:623
Entrez Gene (Gene ID) 623
BindingDB P46663

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.86 0.94 0.9 0.9 0.97 0.81 Download
FP4 fingerprints 0.880 0.850 0.870 0.870 0.930 0.730 Download
MACCS fingerprints 0.780 0.860 0.820 0.810 0.900 0.650 Download
Daylight fingerprints 0.830 0.820 0.830 0.830 0.890 0.650 Download
ECFP2 fingerprints 0.970 0.910 0.940 0.940 0.980 0.880 Download
ECFP4 fingerprints 0.960 0.960 0.960 0.960 0.990 0.920 Download
ECFP6 fingerprints 0.950 0.970 0.960 0.960 0.990 0.920 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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