Target name

P47746: Cannabinoid receptor 1


  Protein function

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca

  Database links

Uniprot primary ID P47746
GRCP SARfari Variant Name mCB1R_1507
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 56
PharmGKB ID
KEGG ID mmu:12801
Entrez Gene (Gene ID) 12801
BindingDB P47746

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.89 0.86 0.86 0.89 0.73 Download
FP4 fingerprints 0.840 0.740 0.790 0.800 0.870 0.580 Download
MACCS fingerprints 0.810 0.740 0.780 0.780 0.830 0.550 Download
Daylight fingerprints 0.620 0.900 0.760 0.720 0.830 0.540 Download
ECFP2 fingerprints 0.900 0.720 0.810 0.830 0.840 0.630 Download
ECFP4 fingerprints 0.910 0.820 0.860 0.870 0.900 0.730 Download
ECFP6 fingerprints 0.910 0.870 0.890 0.890 0.910 0.780 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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