Target name

P47901: Vasopressin V1b receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

  Database links

Uniprot primary ID P47901
GRCP SARfari Variant Name hAVPR1B_196
PDB ID
DrugBank ID DB02638 DB00067 DB00035
BioGrid ID 107034
GuidetoPHARMACOLOGY ID 367
PharmGKB ID PA25188
KEGG ID hsa:553
Entrez Gene (Gene ID) 553
BindingDB P47901

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.88 0.92 0.9 0.9 0.94 0.8 Download
FP4 fingerprints 0.910 0.800 0.860 0.860 0.900 0.720 Download
MACCS fingerprints 0.920 0.760 0.840 0.850 0.890 0.690 Download
Daylight fingerprints 0.770 0.850 0.810 0.800 0.890 0.620 Download
ECFP2 fingerprints 0.930 0.870 0.900 0.900 0.940 0.800 Download
ECFP4 fingerprints 0.930 0.920 0.930 0.930 0.950 0.850 Download
ECFP6 fingerprints 0.900 0.930 0.910 0.910 0.950 0.830 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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