Target name

P47936: Cannabinoid receptor 2


  Protein function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.

  Database links

Uniprot primary ID P47936
GRCP SARfari Variant Name mCB2R_1512
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 57
PharmGKB ID
KEGG ID mmu:12802
Entrez Gene (Gene ID) 12802
BindingDB P47936

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.86 0.88 0.87 0.87 0.91 0.74 Download
FP4 fingerprints 0.760 0.840 0.800 0.790 0.880 0.600 Download
MACCS fingerprints 0.630 0.840 0.740 0.710 0.800 0.480 Download
Daylight fingerprints 0.610 0.930 0.770 0.730 0.900 0.570 Download
ECFP2 fingerprints 0.900 0.860 0.880 0.880 0.930 0.760 Download
ECFP4 fingerprints 0.970 0.880 0.930 0.930 0.940 0.860 Download
ECFP6 fingerprints 0.940 0.890 0.920 0.920 0.940 0.830 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn