Target name

P48974: Vasopressin V1b receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

  Database links

Uniprot primary ID P48974
GRCP SARfari Variant Name rAVPR1B_1518
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 367
PharmGKB ID
KEGG ID
Entrez Gene (Gene ID)
BindingDB P48974

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.75 0.88 0.82 0.8 0.9 0.64 Download
FP4 fingerprints 0.640 0.730 0.690 0.670 0.800 0.370 Download
MACCS fingerprints 0.690 0.710 0.700 0.690 0.830 0.390 Download
Daylight fingerprints 0.680 0.840 0.760 0.740 0.840 0.520 Download
ECFP2 fingerprints 0.870 0.800 0.830 0.840 0.890 0.670 Download
ECFP4 fingerprints 0.890 0.820 0.850 0.860 0.920 0.710 Download
ECFP6 fingerprints 0.880 0.840 0.860 0.860 0.920 0.720 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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