Target name

P49682: C-X-C chemokine receptor type 3


  Protein function

Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:

  Database links

Uniprot primary ID P49682
GRCP SARfari Variant Name hCXCR3_204
PDB ID
DrugBank ID
BioGrid ID 109094
GuidetoPHARMACOLOGY ID 70
PharmGKB ID PA35049
KEGG ID hsa:2833
Entrez Gene (Gene ID) 2833
BindingDB P49682

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.86 0.85 0.85 0.92 0.7 Download
FP4 fingerprints 0.750 0.760 0.750 0.750 0.840 0.510 Download
MACCS fingerprints 0.890 0.750 0.820 0.830 0.880 0.640 Download
Daylight fingerprints 0.770 0.880 0.820 0.810 0.890 0.650 Download
ECFP2 fingerprints 0.950 0.850 0.900 0.900 0.940 0.800 Download
ECFP4 fingerprints 0.960 0.890 0.920 0.920 0.960 0.840 Download
ECFP6 fingerprints 0.960 0.900 0.930 0.930 0.960 0.860 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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