Target name

P49684: Urotensin-2 receptor


  Protein function

High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P49684
GRCP SARfari Variant Name rGPR14_1526
PDB ID
DrugBank ID
BioGrid ID 248616
GuidetoPHARMACOLOGY ID 365
PharmGKB ID
KEGG ID rno:57305
Entrez Gene (Gene ID) 57305
BindingDB P49684

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.92 0.86 0.89 0.89 0.94 0.78 Download
FP4 fingerprints 0.880 0.870 0.870 0.870 0.910 0.740 Download
MACCS fingerprints 0.870 0.870 0.870 0.870 0.930 0.730 Download
Daylight fingerprints 0.870 0.930 0.900 0.890 0.920 0.800 Download
ECFP2 fingerprints 0.830 0.850 0.840 0.840 0.880 0.670 Download
ECFP4 fingerprints 0.880 0.930 0.900 0.900 0.920 0.810 Download
ECFP6 fingerprints 0.900 0.940 0.920 0.920 0.930 0.840 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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