Target name

P50052: Type-2 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

  Database links

Uniprot primary ID P50052
GRCP SARfari Variant Name hAGTR2_207
PDB ID
DrugBank ID DB01349
BioGrid ID 106692
GuidetoPHARMACOLOGY ID 35
PharmGKB ID PA44
KEGG ID hsa:186
Entrez Gene (Gene ID) 186
BindingDB P50052

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.83 0.94 0.88 0.88 0.94 0.77 Download
FP4 fingerprints 0.810 0.820 0.820 0.820 0.900 0.630 Download
MACCS fingerprints 0.790 0.880 0.830 0.830 0.900 0.670 Download
Daylight fingerprints 0.820 0.870 0.850 0.840 0.890 0.690 Download
ECFP2 fingerprints 0.860 0.920 0.890 0.880 0.940 0.770 Download
ECFP4 fingerprints 0.850 0.930 0.890 0.890 0.950 0.790 Download
ECFP6 fingerprints 0.840 0.940 0.890 0.890 0.950 0.780 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn