Target name

P50130: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P50130
GRCP SARfari Variant Name susDRD1_1529
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ssc:100144487
Entrez Gene (Gene ID) 100144487
BindingDB P50130

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.82 0.83 0.82 0.82 0.89 0.65 Download
FP4 fingerprints 0.920 0.690 0.810 0.820 0.850 0.630 Download
MACCS fingerprints 0.860 0.680 0.770 0.790 0.840 0.540 Download
Daylight fingerprints 0.780 0.820 0.800 0.790 0.880 0.600 Download
ECFP2 fingerprints 0.930 0.790 0.860 0.870 0.880 0.730 Download
ECFP4 fingerprints 0.950 0.840 0.890 0.900 0.930 0.790 Download
ECFP6 fingerprints 0.940 0.860 0.900 0.900 0.930 0.800 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn