Target name

P51685: C-C chemokine receptor type 8


  Protein function

Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.

  Database links

Uniprot primary ID P51685
GRCP SARfari Variant Name hCCR8_215
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 65
PharmGKB ID PA26173
KEGG ID hsa:1237
Entrez Gene (Gene ID) 1237
BindingDB P51685

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.87 0.87 0.87 0.87 0.94 0.74 Download
FP4 fingerprints 0.790 0.820 0.810 0.800 0.890 0.610 Download
MACCS fingerprints 0.580 0.870 0.720 0.670 0.890 0.460 Download
Daylight fingerprints 0.630 0.960 0.790 0.750 0.940 0.620 Download
ECFP2 fingerprints 0.850 0.850 0.850 0.850 0.940 0.700 Download
ECFP4 fingerprints 0.880 0.920 0.900 0.900 0.970 0.810 Download
ECFP6 fingerprints 0.880 0.930 0.910 0.900 0.970 0.810 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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