Target name

P61168: D(2) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P61168
GRCP SARfari Variant Name mDRD2_1558
PDB ID
DrugBank ID
BioGrid ID 199306
GuidetoPHARMACOLOGY ID 215
PharmGKB ID
KEGG ID mmu:13489
Entrez Gene (Gene ID) 13489
BindingDB P61168

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.89 0.63 0.76 0.79 0.84 0.53 Download
FP4 fingerprints 0.900 0.640 0.770 0.800 0.770 0.560 Download
MACCS fingerprints 0.890 0.670 0.780 0.800 0.820 0.570 Download
Daylight fingerprints 0.740 0.610 0.670 0.700 0.710 0.350 Download
ECFP2 fingerprints 0.890 0.620 0.760 0.790 0.770 0.540 Download
ECFP4 fingerprints 0.920 0.690 0.800 0.820 0.840 0.620 Download
ECFP6 fingerprints 0.920 0.720 0.820 0.830 0.850 0.650 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn