Target name

P61169: D(2) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P61169
GRCP SARfari Variant Name rDRD2_1559
PDB ID
DrugBank ID
BioGrid ID 246498
GuidetoPHARMACOLOGY ID 215
PharmGKB ID
KEGG ID rno:24318
Entrez Gene (Gene ID) 24318
BindingDB P61169

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.83 0.69 0.76 0.77 0.83 0.52 Download
FP4 fingerprints 0.870 0.680 0.770 0.790 0.830 0.560 Download
MACCS fingerprints 0.810 0.640 0.730 0.750 0.800 0.460 Download
Daylight fingerprints 0.720 0.640 0.680 0.690 0.730 0.360 Download
ECFP2 fingerprints 0.900 0.750 0.830 0.840 0.900 0.660 Download
ECFP4 fingerprints 0.910 0.800 0.860 0.860 0.920 0.720 Download
ECFP6 fingerprints 0.880 0.810 0.850 0.850 0.920 0.700 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn