Target name

P70536: Oxytocin receptor


  Protein function

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P70536
GRCP SARfari Variant Name rOXTR_1566
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 369
PharmGKB ID
KEGG ID rno:25342
Entrez Gene (Gene ID) 25342
BindingDB P70536

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.9 0.83 0.86 0.87 0.91 0.73 Download
FP4 fingerprints 0.820 0.850 0.830 0.830 0.890 0.670 Download
MACCS fingerprints 0.740 0.830 0.790 0.770 0.890 0.570 Download
Daylight fingerprints 0.760 0.910 0.830 0.820 0.920 0.680 Download
ECFP2 fingerprints 0.900 0.900 0.900 0.900 0.950 0.800 Download
ECFP4 fingerprints 0.910 0.900 0.910 0.910 0.960 0.820 Download
ECFP6 fingerprints 0.910 0.920 0.910 0.910 0.960 0.820 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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