Target name

Q00788: Vasopressin V2 receptor


  Protein function

Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

  Database links

Uniprot primary ID Q00788
GRCP SARfari Variant Name rV2R_1592
PDB ID 2JX4
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 368
PharmGKB ID
KEGG ID rno:25108
Entrez Gene (Gene ID) 25108
BindingDB Q00788

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.74 0.85 0.8 0.79 0.87 0.6 Download
FP4 fingerprints 0.700 0.680 0.690 0.690 0.790 0.380 Download
MACCS fingerprints 0.840 0.740 0.790 0.800 0.870 0.590 Download
Daylight fingerprints 0.760 0.850 0.800 0.800 0.870 0.610 Download
ECFP2 fingerprints 0.840 0.800 0.820 0.830 0.880 0.650 Download
ECFP4 fingerprints 0.850 0.840 0.850 0.850 0.910 0.690 Download
ECFP6 fingerprints 0.840 0.850 0.850 0.850 0.910 0.690 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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