Target name

Q15077: P2Y purinoceptor 6


  Protein function

Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID Q15077
GRCP SARfari Variant Name hP2RY6_227
PDB ID 2B6R
DrugBank ID
BioGrid ID 111070
GuidetoPHARMACOLOGY ID 326
PharmGKB ID PA32872
KEGG ID hsa:5031
Entrez Gene (Gene ID) 5031
BindingDB Q15077

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.92 0.47 0.7 0.75 0.69 0.44 Download
FP4 fingerprints 0.880 0.540 0.710 0.750 0.600 0.450 Download
MACCS fingerprints 0.940 0.430 0.690 0.750 0.660 0.440 Download
Daylight fingerprints 0.880 0.500 0.690 0.740 0.690 0.400 Download
ECFP2 fingerprints 0.930 0.420 0.680 0.740 0.500 0.410 Download
ECFP4 fingerprints 0.920 0.420 0.670 0.740 0.610 0.400 Download
ECFP6 fingerprints 0.920 0.460 0.690 0.750 0.650 0.430 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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