Target name

Q15761: Neuropeptide Y receptor type 5


  Protein function

Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

  Database links

Uniprot primary ID Q15761
GRCP SARfari Variant Name hNPY5R_231
PDB ID 2HE6
DrugBank ID
BioGrid ID 110949
GuidetoPHARMACOLOGY ID 308
PharmGKB ID PA31742
KEGG ID hsa:4889
Entrez Gene (Gene ID) 4889
BindingDB Q15761

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.82 0.91 0.87 0.86 0.93 0.74 Download
FP4 fingerprints 0.830 0.790 0.810 0.810 0.890 0.610 Download
MACCS fingerprints 0.780 0.770 0.770 0.770 0.840 0.550 Download
Daylight fingerprints 0.750 0.920 0.830 0.820 0.910 0.680 Download
ECFP2 fingerprints 0.920 0.900 0.910 0.910 0.960 0.830 Download
ECFP4 fingerprints 0.930 0.960 0.950 0.950 0.980 0.900 Download
ECFP6 fingerprints 0.910 0.970 0.940 0.940 0.970 0.880 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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