Target name

Q16581: C3a anaphylatoxin chemotactic receptor


  Protein function

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

  Database links

Uniprot primary ID Q16581
GRCP SARfari Variant Name hC3AR1_234
PDB ID
DrugBank ID
BioGrid ID 107180
GuidetoPHARMACOLOGY ID 31
PharmGKB ID PA25898
KEGG ID hsa:719
Entrez Gene (Gene ID) 719
BindingDB Q16581

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.86 0.72 0.79 0.8 0.84 0.58 Download
FP4 fingerprints 0.880 0.720 0.800 0.810 0.800 0.610 Download
MACCS fingerprints 0.710 0.760 0.730 0.730 0.830 0.470 Download
Daylight fingerprints 0.830 0.780 0.800 0.810 0.860 0.610 Download
ECFP2 fingerprints 0.750 0.740 0.740 0.750 0.780 0.490 Download
ECFP4 fingerprints 0.890 0.770 0.830 0.840 0.830 0.670 Download
ECFP6 fingerprints 0.900 0.780 0.840 0.850 0.860 0.690 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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